KMID : 1035620180060030161
|
|
Allergy Asthma & Respiratory Disease 2018 Volume.6 No. 3 p.161 ~ p.167
|
|
The association between nasal eosinophilia and aeroallergen sensitization in children and adolescents with rhinitis
|
|
Yang Eun-Ae
Park Yu-Mi Kim Kyung-Hoon Lee Hye-Jin Kim Hwan-Su Chun Yoon-Hong Yoon Jong-Seo Kim Hyun-Hee Kim Jin-Tack
|
|
Abstract
|
|
|
Purpose: To identify the correlation between nasal eosinophilia and aeroallergen sensitization in children and adolescents.
Methods: This is a retrospective study of patients below 18 years of age who had a history of rhinitis that lasted more than 2 weeks or had been repeated more than once a year, received nasal eosinophil examinations, and had serum specific IgE to aeroallergens measured at an Allergy Clinic in a single tertiary teaching hospital in Seoul, Korea. The percentage of nasal eosinophils was calculated by the number of eosinophils per total leukocytes in a high-power field of 1,000¡¿. Data was analyzed to determine the association between nasal eosinophilia and 18 aeroallergens.
Results: Of the 245 patients included, 156 (63.7%) were male and the mean age (¡¾standard deviation) was 7.9 years (¡¾3.8). In total, 175 patients (71.4%) were sensitized to at least 1 of the 18 aeroallergens tested, and sensitization to house dust mite was most common. In addition, 118 (48.2%) and 69 patients (28.2%) had nasal eosinophilia of at least 1% and 5%, respectively. There were no significant correlations between serum total IgE or age and the percentage of nasal eosinophils. However, the percentage of nasal eosinophils in the group sensitized to any aeroallergens was significantly increased compared to the nonsensitized group (P=0.002). The percentage of nasal eosinophils was significantly higher in patients who were sensitized to Birch-Alder Mix, oak white, Bermuda grass, orchard grass, timothy grass, sweet vernal grass, rye, mugwort, short ragweed, Alternaria alternata, cats, dogs or Dermatophagoides farinae compared to those nonsensitized.
Conclusion: Nasal eosinophilia was significantly associated with sensitization to aeroallergens.
|
|
KEYWORD
|
|
Eosinophilia, Allergen, Child, Rhinitis
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|